Tbx1 Regulates Proliferation and Differentiation of Multipotent Heart Progenitors
نویسندگان
چکیده
منابع مشابه
Tbx1 regulates proliferation and differentiation of multipotent heart progenitors.
RATIONALE TBX1 encodes a T-box transcription factor implicated in DiGeorge syndrome, which affects the development of many organs, including the heart. Loss of Tbx1 results into hypoplasia of heart regions derived from the second heart field, a population of cardiac progenitors cells (CPCs). Thus, we hypothesized that Tbx1 is an important player in the biology of CPCs. OBJECTIVE We asked whet...
متن کاملMolecular Medicine Tbx1 Regulates Proliferation and Differentiation of Multipotent Heart Progenitors
Rationale: TBX1 encodes a T-box transcription factor implicated in DiGeorge syndrome, which affects the development of many organs, including the heart. Loss of Tbx1 results into hypoplasia of heart regions derived from the second heart field, a population of cardiac progenitors cells (CPCs). Thus, we hypothesized that Tbx1 is an important player in the biology of CPCs. Objective: We asked whet...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2009
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.109.200295